Hornady Dangerous Game Series ammunition is designed specifically for large game and safari hunting. These cartridges feature both classic bullets, like the 270 gr InterLock Spire Point-Recoil Proof, as well as our new flagship DGS  . All ammunition is designed to work well in all rifles, and meticulous attention was devoted to ensure that ammunition like the 450/400 Nitro Express 3", and 450 Nitro Express 3-1/4" regulate properly in both classic doubles and their younger counterparts.