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Raphiel, No. The Ruger LCP was not designed for use with +P ammunition. Given the LCP's lightweight and compact design, the use of +P ammunition in this particular model may result damage to the firearm or personal injury. ---- defensivecarry.com/threads/rugers-answer-to-p-in-the-lcp.83982/

Someone asked this question on Buffalo Bores website and Buffalo Bore says their +p ammo is good to go in an LCP
"1. Can I shoot your +P 380 Auto ammo in my LCP?
Yes you can. Gun makers often warn against using any ammo that is not SAAMI spec. and there is no SAAMI spec. for the 380 auto +P cartridge. Gun makers do this to protect themselves from any liability in our super litigious American society.
Buffalo Bore and others have tested our 380 auto +P ammo in the LCP and many LCP owners currently shoot our +P ammo in their LCPs and we've never heard of any problems from the "power" or "pressure" of the ammo, but obviously the use of +P ammo in these little guns should be limited to just enough to test reliable feeding and point of impact, then carry the ammo in your LCP in the event you need it, but don't go plinking with it."
buffalobore.com/ammo/QA.html