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Hi Eric and welcome. Yes, the Glock 45 and Glock 19 use the same barrel, as both have a standard 4.02-inch barrel length and are interchangeable. Cheers, stay safe and enjoy!

Yes, it will fit & function properly in the GL45. Glock 19 and Glock 45 are very similar pistols with the same barrel length and sight radius, the key difference lies in the grip size