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Hope all is well George. The Viridian 912-0024 E-Series Laser Sight is designed specifically for compact and subcompact pistols. Since your Walther PPQ M2 22 falls between a compact/full size, YES this will fit and will retain that low profile look. Take care George and may you and your family enjoy the rest of these Happy Holidays!!

Hi George and welcome. It will fit no issue. A two for one "Combo Laser Light" for your consideration here: https://www.budsgunshop.com/product_info.php/products_id/173313/olight+baldr+mini+rl+weapon+light+with+red+laser+for+picatinny+rail+black ---------- Just do a youtube search on the clever ratchet system for fitment to all sized handguns. Cheers, stay safe and enjoy!