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Hi Christopher and welcome. Yes but, I would check out this thread (may need shorter mounting screws): https://www.reddit.com/r/Glocks/comments/llw3h0/psa_glock_43x48_mos_w_sig_romeo0_issue/ --------- Cheers, stay safe and enjoy!

Hi Christopher, yes sir, the Romeo Zero uses the RMSc footprint, just like the Glock 48 MOS Stay safe & have a great day!