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Hi David, no sir, there is no .22wmr cylinder available for this gun. Stay safe & have a great day!

Hi David and welcome. Unfortunately, no Sir. The Single Six Convertible may be an option: https://www.budsgunshop.com/product_info.php/products_id/70101/ruger+0623+single-six+convertible+6rd+22lr+22mag+4.62 - Cheers and stay safe!

sorry Ruger never made a 22 mag cylinder for the single 10 they do have convertible single 6 models https://www.budsgunshop.com/product_info.php/products_id/70101/ruger+0623+single-six+convertible+6rd+22lr+22mag+4.62 or check out the Rough rider guns from Heritage