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Good evening to you!! Sorry but no, the S&W22 shoots 22 magnum only. A 22lr will not cycle the weapon. Nor feed from the magazine. Hope this helps. Have a good rest of your day.

Hi Manuel and welcome. No Sir. 22 Magnum will not chamber 22LR, it would just slide down the barrel. This is the reason combo 22Mag/22LR revolvers come with two cylinders - https://www.budsgunshop.com/product_info.php/products_id/87903/heritage+manufacturing+rough+rider+22lr+22mag+4.75+blued --------------- Cheers and stay safe!

Good evening to you!! Just some information on the 22lr and 22wmr in comparison. The .22 WMR (Winchester Magnum Rimfire) is dimensionally larger than the .22 LR (Long Rifle), both in terms of case length and width. The .22 WMR has a longer case and a wider base diameter, making it incompatible with firearms chambered for .22 LR. Here's a more detailed comparison: .22 LR: Bullet Diameter: .223 inches Rim Diameter: .278 inches Case Length: .613 inches Overall Length: 1 inch .22 WMR: Bullet Diameter: .224 inches Rim Diameter: .294 inches Case Length: .942 inches Overall Length: 1.35 inches Have a good rest of your day.

22 Magnum will not chamber a 22LR!

Hi Manuel, no sir, .22lr and .22 magnum are completely different calibers and are not interchangeable. Stay safe & have a great day!

No, and please don't try.