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Hi Cody and welcome back. I think you mean more powerful caliber as .45 ACP is fairly large. 10mm would fill the bill nicely and can pull double duty for self-defense and hunting: You can find your capacity and price range in a 10mm handgun here: https://www.budsgunshop.com/search.php/type/firearms/caliber/10000587-10mm
10mm is the new "Go To" caliber with regards to stopping power.
Good evening to you!! As everyone is saying the 10mm is the old new cartridge again. I carry a S&W M&P in 10mm and a Colt Delta Elite in 10mm. Can't beat it without going overboard. Then again I carry a M&P in 40 S&W too. Same diameter bullet same weight bullets as a 10mm with out the recoil of the 10. Either is good on two legged and 4 legged predators. Hope this helps. Have a good rest of your day.