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Yes, depending on the S&W speedloader you choose, example: can't use a 5rd loader on a k6 obviously. But if its the right model that matches your frame, it will work fine. Colt detective speed loader would be you're best bet though, if your not a fan of the speedstrip.

http://kimbertalk.com/forums/kimber-revolver-forum/20681-k-frame-speedloader.html