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I doubt it. Unless it's a normal P226 frame with a conversion kit installed, the internals are likely completely different.

Yes, the kits are wildly popular and this will work fine.

Yes.Using a SIG SAUER Caliber X-Change Kit, the P226-22 is convertible to 9mm, .357SIG, or .40S&W. https://www.sigsauer.com/store/p226-22-nitron-full-size.html