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I like my Bianchi Cyclone for my 686. http://www.safariland.com/products/holsters-and-gear/holsters/sporting-holsters/belt-slide/model-111-cyclone-belt-holster-10814.html#start=1

Since you didn't specify, I'll give you a couple of alternatives. www.amazon.com/Tagua-DCH-1218-Holster-Ruger-GP100/dp/B011LXKI6K for IWB, and www.safariland.com/products/holsters-and-gear/holsters/concealable-holsters/belt-slide/model-6287-sls-belt-slide-concealment-holster-11146.html?dwfrm_holsterfinder_gunid=275946&dwfrm_holsterfinder_lightid=&dwfrm_holsterfinder_addonid=&dwfrm_holsterfinder_guntype=revolver&dwfrm_holsterfinder_manufacturer=Ruger&dwfrm_holsterfinder_model=GP100&dwfrm_holsterfinder_barrellength=4.50&dwfrm_holsterfinder_caliber=.357+Mag&dwfrm_holsterfinder_haslight=&dwfrm_holsterfinder_lighttype=&dwfrm_holsterfinder_hasaddon=&dwfrm_holsterfinder_addontype= for OWB I hope this helps Robert. I have both Bianchi holsters and Tagua Holsters and both are very serviceable and well made.

the Bianchi or Don Hume holsters are very good

Robert, there are several options : https://www.budsgunshop.com/catalog/product_info.php/products_id/711010599/evolution+2+series+paddle+holster+for+ruger+gp100+black+right+ha ----- https://www.budsgunshop.com/catalog/product_info.php/products_id/722025299/summer+comfort+inside+pant+holster+%7c+black+%7c+right ------ https://www.budsgunshop.com/catalog/product_info.php/products_id/711010843/silhouette+holster+for+colt+king+cobra%2fpython%2fsmith+%26+wesson+l+f