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No it will not as there is no top rail to attach it to

Joseph, like the other answer said the SR9C has no top rail and even if you did have a mounting solution for it this sight would be quite comically large for a pistol that size, here's some perspective with a full size Glock: https://www.glockstore.com/assets/images/products/Truglo-Multi-Reticle-Dual-Color-Open-Red-Dot_main-3.jpg?resizeid=7&resizeh=275&resizew=275 If you did get slide milling a or dovetail adapter to mount a red dot you would be looking more for the form factor of a Burris Fastfire, Trijicon RMR, Leupold Deltapoint, Vortex Venom, Sig Romeo1, etc.

It does wok well on my ruger 22/45 (stationary rail) I think that even if you could mount it to a SR9c slide the weight may be enough to cause failure to chamber issues by slowing down the slide

Joseph, no Sir it will not. You would need a Weaver or Picatinny Style Rail to mount this and the Ruger SR9c just does not have this option.