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Theodore, no Sir, most will not. I am sure a semi-auto could be modified to be more reliable with subsonics.

some will and some will not the only way to know for sure is to try them

Theodore, What do you need subsonic 22lr. Normal 22lr is below the speed of sound at 1125 fps. Some standard rounds may go to 1170 fps. Sub sonic 22 lr rounds are not worth the hassle.