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Irv, You can fire .556 round in this firearm no problem. It will handled added pressure no issue.

I would follow the Savage recommendations of it being ONLY a 223 but I would also contact Savage to verify this PHONE US: (413) 568-7001 or (800) 370-0708

Irv, the nature of this rifle is accuracy and it will be head spaced for greatest accuracy with 223 ammunition. I would recommend following the Maunfacturer's recommendation of 223 ammunition.