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Daniel, the general consensus is no since the barrel is stamped .223 Remington. For safety and warranty reasons I would ask CZ-USA Customer Service directly at Toll-free: 1-800-955-4486 or Phone: (913) 321-1811 Extension: 4701

.223 0nly CZ USA 527 Carbine Bolt Action Rifle (Blued) Specifications and Features: CZ USA 03059 Right Hand Bolt Action Rifle .223 Remington 18.5" Cold Hammer Forged Barrel 1:9" Twist Rate 5 Rounds Detachable Box Magazine Single Set Trigger Two Position Safety Fixed Sights Integrated 16mm Scope Bases Carbine Style Synthetic Style Stock Recoil Pad Sling Swivel Studs 13.46" Length Of Pull Overall Length 37.4" Overall Weight 5.94lbs Black Finish (Stock) Blued Finish (Metalwork) Includes: One 5 Round Detachable Box Magazine