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Depending on what you want to use it for.. The Glock 19 is much lighter,easier to carry while the SP-01 is bigger and heavier making it a softer shooting pistol. CZ also has .22LR conversion uppers for them to shoot inexpensive .22 ammo. They're both gold standards in reliability and quality, no reason you can't own both. :)

Ed, the CZ-USA SP-01 will be the more ergonomic Pistol Sir in grip comfort and point-ability. Functionally they are close so it will boil down to which feels best to you. I would take a trip to a local gun shop and decide for yourself first hand. Cheers!

Ed, The guns are different manual of arms. They are two different firearms. The G19 is a striker fired gun. No manual safety. Polymer lower. Trigger fin safety. Much lighter and 22 degree angle on grip. SP-01 is DA/SA- double action-single action. All metal. Manual safety. May have decocker option. Less angle on grip that many say is more ergonomic and points more naturally. Heavier. Both great guns, but two different guns. Try to get your hands on both and compare.

that will depend on which you like and shoot the best I suggest you go to a local range and rent one of each and see which works best for you