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Rob, the 629 will have no problems Sir. However, for warranty and safety reasons, I would ask Smith and Wesson Customer Service directly at (USA) 1-800-331-0852 - Mon-Fri 8:00AM-6:00PM Eastern Time

Rob, This S&W beauty will handle any 44 magnum load you can find. It will handle the 300+grain loads better then the shooter will.

it will be fine however the heavier the load the more wear on the gun it will cause