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Phillip, The Grip Panels are the absolute same size Sir. .45, 9mm, 380, 22 does not matter.

Honey, though not an accurate answer I do think it will work. The bullets might be different but the grips should be the same.

Yo brotha you can change these grips back a forth to your 22. Browning.com has them listed for both handguns my brotha.

They'll fit