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Pamela, not without some modification. The holes for the grip bushings are slightly larger than a standard 1911. Details of modification for fitment to the 22/45 is here : https://www.texasguntalk.com/threads/fit-a-set-of-standard-1911-grips-to-my-ruger-mkiv-22-45-it-can-be-done.84487/

yes they will fit I have the 1911 Hogue wraparound grips on mine