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Bradford, Yes. This model has the manual thumb safety. It is not ambidextrous. Only on left side of pistol.

yes it has the thumb safety on the left side (I own this gun) I will tell you the thumb safety is very small and I worry about using it under stress

Bradford, yes Sir, this UPC code has the Manual Thumb Safety. It includes: - Crimson Trace Integrated Red Laser with Ambidextrous Activation, On/Pulse/Off Modes, 4 Hour Constant On Battery Life and Uses Two #357 Silver Oxide Batteries.