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Judy, not a Ruger but a similar 22 Pistol and had feeding issues due to low power. Only a quarter of them would cycle. These are best for rifles or single shots. Ruger SR-22 Owners that have shot these through their pistols can confirm : http://rugerforum.com/phpBB3/viewtopic.php?f=3&t=177403

I've used CCI stingers in a 22lr pistol They are expensive for 22lr and should be used as deffensive carry ammo, then you can use bulk bucket of ammo for range practice on stock here http://exammo-com.3dcartstores.com/CCI-Stinger-Ammunition-22-Long-Rifle-32-Grain-Plated-Lead-Hollow-Point-Box-of-50_p_21.html