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They'll shoot but they'll not pattern well, as they are designed to be fired out of smooth bore rifle.

Robert, yes Sir, I do it all the time. Expect effective range to be 8 to 10 feet. They are counter intuitive to shotguns as the shorter the rifled barrel of the pistol/rifle, the better the pattern : https://www.youtube.com/watch?v=YxphDh9ydII&t=530s