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It is very unlikely that these shotshells have enough energy to cycle a semi auto of any kind. Even if that weren't the case, #12 shot from a short rifled barrel is likely to spread rapidly outside the muzzle and provide very little accuracy.

Trevor pretty much nailed it on this one, available "standard 22lr ammo" is available here https://www.ammobuy.com/ammo/22lr

Joseph, no Sir. The 22lr shot does not produce sufficient recoil to reliably cycle the slide. Cheers and stay safe!

Joseph, no Sir. The 22lr shot does not produce sufficient recoil to reliably cycle the slide. Cheers and stay safe!