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Yes J.C.. Other than the charging lever being on the right side, the actual shooting is ergonomicly friendly to LH shooters as well. I'm starting to see a trend of firearm makers implementing ambidextrous controls or the ability to move controls to either side of firearms these days. -- http://www.ruger.com/products/22Charger/models.html

Yes they are, I've noticed more company's are doing the same.