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Joseph, some owners have said the Single Six 22 Mag Cylinder works and a few said no. I would read here and contact Ruger for advice : https://www.rugerforum.com/phpBB3/viewtopic.php?t=293235
No, the Wranglers only in 22lr. If you want a good but inexpensive 22lr and mag revolver I own the heritage rough rider and for being a cheaper pistol it's actually great and very accurate. Hope this helps.
No wrangler but the Single 9 is available in 22wmr https://www.budsgunshop.com/product_info.php/products_id/83632/ruger+8150+single-nine+9rd+22+mag++65
Its not offered by Ruger if you want 22 Mag go with the single six combo or the Heritage Rough rider combo
