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YES, the revolver can chamber both 454 Casull and 45 Colt ammunition. It is listed as .460 S&W Magnum/.454 Casull/.45 Colt. I hope this helps!
Yes, this can shoot all 3. Obviously 460 S&W, 454 casull, and 45 long Colt. There's some good demonstration videos showing this shooting all 3. Hope this helps.
Yes, A .460 S&W will also chamber and shoot a .454 Casull and a .45 Colt.
Charles, yes Sir. No issues with either whatsoever. This one revolver allows you to fire four different calibers starting with its namesake the .460 S&W Magnum followed by the .454 Casull, .45 Colt and the .45 S&W Schofield. ------------- Good details here : https://www.ammoland.com/2014/05/smith-wesson-460xvr-revolver/#axzz74OLZT2Vd
yes it is safe with all 3