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Jeremy, from the PPK Owners Manual : "Plus-P" (+P) ammunition generates pressures in excess of the pressures associated with standard ammunition. Such pressures may affect the wear characteristics of your PPX pistol or exceed the margin of safety. Use of "Plus-P" ammunition may result in the need for more frequent service. Basically yes but, infrequently with more frequent cleaning and inspection intervals.
Itll run +p but should be done sparingly. Plus P ammo is going to make shooting much less manageable put of such a small gun id look at some standard pressure federal HST, as it will much more pleasant to shoot out of this gun and will cause significantly less wear and tear. Hst is out of stock at buds right now but hit the notify me when available button to receive an email when they come back in stock https://www.budsgunshop.com/product_info.php/products_id/98167/federal+p380hst1s+premium+personal+defense+hst+micro+380+acp -------------------- Or federal Punch and Hdrashock are in stock here https://ammoseek.com/ammo/380-auto/Federal?ekw=.380ACP
you can use it but I would only use enough to be sure it is reliable and accurate enough for self defense then shoot standard 380 loads reserving the +p for when NEEDED