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Craig, FNX-45 Tactical handguns are chambered for the .45 ACP cartridge and are compatible with all ammunition loaded to U.S. Industry Standards, including +P and hollow-point loads. .45 ACP ammunition manufactured in accordance with NATO, U.S., SAAMI, or CIP standards is within the design limits and known to function in the handgun. FN's are Commercial, Law Enforcement, and Military rated pistols. Have a great day!