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No, this is 380 acp and is a completely different caliber. So it won't work in your 38 S&W pistol. Sorry but hope this helps.

Euyless, no Sir, this is a rimless cartridge. You would need .38 Special (if the caliber of your S&W pistol) : https://www.budsgunshop.com/search.php/type/Ammunition/caliber/10000566-38+Special