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Jonathon, no, this is for use with 9mm only. Have a great day!

No. Direct quote from this question being asked on sig talk. "Got the same reply. That said was advised by SIG CS that you cannot go from a 9mm slide to a 357 or 40 barrel. The barrels won't fit in the 9mm slide." Also grey ghost website says "for use with 9mm ONLY" https://greyghostprecision.com/ggp320-compact-slides/

Jonathon, no, this will only work with 9mm. Unfortunately it won't work with 357 sig. Sorry but hope this helps.

Jonathan, unfortunately no. This is designed specifically for the 9mm **ONLY**. Cheers and stay safe!