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Bobby, no sir, 9mm and 45acp are completely different calibers than 357 & 38. Do not try it. I guess you are asking because of this description >>> budsgunshop.com/product_info.php/products_id/115401/bond+arms+roughneck+.357+2.5 ......that just means those are the calibers this gun comes in, one gun will NOT shoot all those calibers. The gun above will shoot 357 magnum or .38 special. This one will shoot 9mm budsgunshop.com/product_info.php/products_id/113659/bond+arms+roughneck+2.5+9mm .....Stay safe & have a great day!

Hi Bobby and welcome. unfortunately no Sir. The .357 and .38 Special has a specific barrel diameter internally as does the 9mm and 45ACP. It's either .357/38 or 9mm or 45ACP separately. The different calibers can be shot through the derringer with just a barrel Change. All guns have the patented barrel interchange system, which means that once you buy any gun, you have the option of 14 different barrels and with those, a choice of 24 different cartridges. Example : https://www.budsgunshop.com/product_info.php/products_id/150171/interchangeable+stainless+steel+barrel+for+bond+arms+.45+acp+.45 -------------------------------- https://www.budsgunshop.com/product_info.php/products_id/150170/interchangeable+stainless+steel+barrel+for+bond+arms+9mm ----- Cheers and stay safe!

Bobby, no it can't shoot 9mm or 45acp. It can only fire 357 and 38 special. The description is confusing but it just means they also make them in those calibers. If you decide down the road you want a different caliber like 9mm or 45acp bond arms does make barrels you can swap to change calibers. So you just have to purchase a different Barrel and swap it to change calibers. Hope this helps.

Hi Bobby, I certainly can understand you questioning the ability of this model to shoot 9mm & .45 ACP based on the description. They should have worded it differently. Short answer here is a resounding NO, it will ONLY shoot .357 & .38. Those are a different size than both 9mm & .45.