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Mike, no sir, no manual safety on this model. The model with thumb safety is here budsgunshop.com/product_info.php/products_id/144260/sig+sauer+365-380-bss-ms+p365+380+acp+3.10+10+1+stainless+steel+frame+black+nitron+stainless+steel+slide+with+optics+cut+black , This is the same exact gun with safety. Stay safe & have a great day!