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Hi Ken and welcome. No. The 3-inch barrel is chambered to fire . 45 Colt and up to 2.5" . 410 shot shells. Cheers and stay safe!

No, only goes up to 2.5" 410 shells in that model.

Ken, it is chambered only for 2 1/2" shells. https://www.budsgunshop.com/product_info.php/products_id/65826/winchester+410+ga.+2+1+2+3+pellets+000+lead+buckshot , I recommend Hornady Critical Defense for self defense https://www.budsgunshop.com/product_info.php/products_id/84263/hornady+critical+defense+.410+ga+fxt+slug+with+flex+tip+20rd+box , Stay safe & have a great day!