Ask the Community

Hi James and welcome. It will but this is a +P loading that Henry does not recommend firing a steady diet of. Cheers and stay safe! https://www.henryusa.com/the-henry-repeater/when-the-hunting-was-bad/#:~:text=Henry%20Repeating%20Arms%20manufactures%20a,Long%20Colt%20Plus%20P%20ammunition.

James, I wouldn't try it. This is what Henry has to says about heavy grain Projectiles............ Big Boys chambered for either .44 Magnum or .45LC, you can use any reputable brand of the standard and +P factory loads, with standard profile bullets (round-nose, flat-nose, and hollow-point), up to maximum projectile weight of 260-grains, and which conforms to SAAMI specs. The rate of twist is 1:38. This does not matter for the larger rounds as our Big boy rifles are not made to be able to safely or properly feed rounds with bullet weights over 270 gr. Our Big Boy's can handle all the +P pressure out there even Big Buffalo Bore ammunition as long as the rounds are not to big (over 270 gr.) to feed through the action."................... Since this is 325 grain I'd imagine it won't feed properly. Sorry but hope this helps.

James, no sir, Big boy rifles are not made to be able to safely or properly feed rounds with bullet weights over 270 gr. The Big Boy's can handle all the +P pressure out there even Big Buffalo Bore ammunition as long as the rounds are not to big (over 270 gr.) to feed through the action. Stay safe & have a great day!