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No, this will not chamber 22Magnum nor fire it Vincent.

No, the 22 Magnum is way too long to fit in the magazine or chamber of the pistol. Visual here (22LR left and 22Mag right) : https://i.ytimg.com/vi/RvjB0L6rgLU/maxresdefault.jpg

Hi Vincent, No it will not. You need .22 LR

now it will not the 22 mags is longer and has a fatter (larger diameter case)case to prevent it from chambering in a 22lr gun