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Hi Kody, Yes it Can be used with the takedown model 10/22. It fits any standard Ruger 10/22 receiver with carbine barrel or .920" bull barrel 18.5" or longer. If you feel an answer is helpful please click the green box stating it as the best answer. We are rated on our answers and are just volunteers. You can choose more then one Thank you!

This will fit like a glove. Fits to any standard Ruger 10/22 receiver with carbine barrel or .920" bull barrel 18.5" or longer. Adapters for standard or heavy barrel included - Easy installation, no gunsmithing needed - Engineered, designed, built and assembled in the U.S.A. - Rail system for mounting optics or other accessories - Accepts most full-capacity magazines including MGW 50-round coffin magazine and the Ruger BX-25® - Ambidextrous charging handle, sling-point mounts, safety and mag release - Integral trigger safety - Adjustable trigger interface to tune to your preference - Included shell deflector allows for full ambidextrous use.

yes it can Fits to any standard Ruger 10/22 receiver with carbine barrel or .920" bull barrel 18.5" or longer. Adapters for standard or heavy barrel included - Easy installation, no gunsmithing needed - Engineered, designed, built and assembled in the U.S.A. - Rail system for mounting optics or other accessories - Accepts most full-capacity magazines including MGW 50-round coffin magazine and the Ruger BX-25® - Ambidextrous charging handle, sling-point mounts, safety and mag release - Integral trigger safety - Adjustable trigger interface to tune to your preference - Included shell deflector allows for full ambidextrous use.