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Hi Zachary, yes, this is Made to fit Optics Ready Smith&Wesson M&P 2.0 C.O.R.E. Fits all calibers of Smith & Wesson Performance 2.0 optics-ready slides. (9mm, 10mm, etc.) Stay safe & have a great day!

I think it will however I suggest you ask C&H https://chpws.com/contact/

Hi Zachary and welcome. Yes Sir. All M&P Core 2.0 pistols including the 10mm have the same optics footprint. Cheers, stay safe and enjoy!