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yes the TX22 can be dry fired with no issues From taurus FAQ see ****** "Dry firing a Taurus .22 pistol or revolver will cause damage to the firing pin. *******This does not include the TaurusTX™ 22 because it is designed to be dry fire safe."

Hi David, yes, the TX22 is designed to be dry fired with no damage to the pistol. Stay safe & have a great day!