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No, there is no manual thumb safety on the left side as seen not present in the listing photo.

Hi William and welcome. There is no Manual Safety on this model. Manual Safety model here : https://www.budsgunshop.com/product_info.php/products_id/154487/sig+p365+manual+safety+9mm+3.1+10rd+black+or

Hi William, no sir, this model does not have a manual thumb safety. Stay safe & have a great day!