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Hi and welcome. No, sights for Glock models 20, 21, 29, 30, 31, 32, 36, 41 are the same. Additionally, sights for Glock models 17, 19, 22, 23, 24, 26, 27, 33, 34, 35, 37, 38, 39 are the same. Therefore, one can see that the Glock 20/21 and G22 sights are not the same size and are not interchangeable. Cheers and stay safe!