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Hi Jermaine and welcome. There are several target loads and self-defense loads that fit the bill. I recommend 186gr target and self-defense jacketed hollow points here: https://www.budsgunshop.com/product_info.php/products_id/63309/cci+blazer+brass+40+s%26w+165+grain+full+metal+jacket+50rd+box ---------------------------------------------- For self-defense: https://www.budsgunshop.com/product_info.php/products_id/60577/fiocchi+40+s%26w+165+grain+jacketed+hollow+point+50rd+box

I'm a big fan of Hornady Critical Duty as my carry rounds. Google the following: 40 S&W 175 gr FlexLock Critical Duty

for practice/targets whatever you can find at a good price For self defense I like federal hydro shoks https://www.budsgunshop.com/product_info.php/products_id/107848/federal+p40hsd1+premium+personal+defense+40+s%26w+165+gr+hydra-shok+deep+hollow+point+20+bx+10+cs

Hi Jermaine, there is no 'best' bullet. For range and target, whatever you can get your hands on is good. For home/self defense, just make sure you use a hollow point bullet https://www.budsgunshop.com/product_info.php/products_id/107848/federal+p40hsd1+premium+personal+defense+40+s%26w+165+gr+hydra-shok+deep+hollow+point+20+bx+10+cs , Stay safe & have a great day!