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Hi Mike, yes sir, this has an ambidextrous manual thumb safety. Stay safe & have a great day!

Hi Mike and welcome. Yes it does. A much better picture of the ambidextrous Manual Safety here: https://www.smith-wesson.com/product/mp57 -------- Cheers, stay safe and enjoy!

Yes, this version has a manual safety.

Yes the m$p 5.7 does have that ambidextrous safety suitable for both left and right hand shooters.