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Hi Steven and welcome. This will fit a Gen 5 no issue. Cheers, stay safe and enjoy!

Constructed using 416R stainless steel with black Nitride finish (compatible with Gen 3 and Gen 4 Glocks). Thread : .578-28 Made In The USA : Made In The USA Length : 5.2 Finish : Black Nitride Item Description : SCO GLK 21 45ACP TB .578X28

Hi Steven, this is compatible with Glock 21 Gen 2, 3, & 4 Stay safe & have a great day!