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Hi Marc and welcome. It can in moderation. BB and other +P loads have more powder, and you will not see a corresponding gain in performance due to the shorter barrel not being able to completely burn the additional powder. You will get higher muzzle flash, recoil/blast and not what you would expect in additional performance. A longer barrel is needed like 4 inches. Stick with standard ammunition for quicker follow up shots. Cheers, stay safe and enjoy!

Can if you want. More wear on components of the pistol.

Hi Marc, this is taken from the Buffalo Bore web site FAQ page - "1. Can I shoot your +P 380 Auto ammo in my LCP? Yes you can. Gun makers often warn against using any ammo that is not SAAMI spec. and there is no SAAMI spec. for the 380 auto +P cartridge. Gun makers do this to protect themselves from any liability in our super-litigious American society. Buffalo Bore and others have tested our 380 auto +P ammo in the LCP and many LCP owners currently shoot our +P ammo in their LCPs and we've never heard of any problems from the "power" or "pressure" of the ammo, but obviously the use of +P ammo in these little guns should be limited to just enough to test reliable feeding and point of impact, then carry the ammo in your LCP in the event you need it, but don't go plinking with it. . Stay safe & have a great day!

You can but...+P isn't the ammo you want to run a full day at the range with. The pressure in +P is higher than a standard load of 95gr which can cause premature wear on the internal parts and more cleaning at closer intervals.