Good afternoon to you!! The Savage Arms Axis in 400 Legend doesn't feature an easy exchangeable barrel. You can have a gunsmith exchange them since it would need to be headspace properly. Hope this helps. Have a good rest of your weekend.

Hi Joseph, you can't just swap the barrels, there would be more involved. It is not made to easily swap barrels.
Stay safe & have a great day!

Hi Joseph and welcome. Yes Sir, depending on the caliber and bolt face requirements of said caliber. Cheers, stay safe and enjoy!