its not a issue for most people here is a quote from a review by a left hand shooter "Expended shells are ejected from the chamber well to the right side. The only time that I have been hit by a spent cartridge is when they bounce off the lane wall at the range." http://guntoters.com/blog/2016/06/12/hi-point-4595ts-carbine-product-review/

Jim, this will depend on your preferred check weld position. This carbine spits the shell casings slightly forward away from the shooter so it should be fine for lefties.