John, correct, this UPC code does not have a Manual Safety Sir.

no this model does not have a thumb safety UPC:
022188871609
Description:
S&W M&P M2.0 45 10R FDE NTS
Brand:
Smith & Wesson
Model:
M&P45 M2.0
Type:
Pistol: Semi-Auto
Caliber:
45AP
Finish:
FDE Stainless Steel Slide
Action:
Double Action Only (Striker Fired Action)
Stock:
FDE Polymer Frame w/S, M, ML, L Inserts
Sight:
Truglo TFX Day Night SIghts
Barrel Length:
4.6
Overall Length:
7.9
Weight:
29.9 oz
Capacity:
10+1
# of Mags:
2
Safety:
Passive Trigger, Striker Block Safety
Receiver:
Polymer with Picatinny-Style Rail
Features:
Ambidextrous Slide Release, Reversible Mag Catch;
Aggressive Texture, Truglo TFX Day/Night Sights

John, No manual thumb safety on this firearm.