Matthew, accuracy is not affected by much at all. With heavy loads, it is just a matter of how long you can recover sight picture for accurate follow up shots. Just practice and your initial group spread will shrink dramatically. Once you get to a desired level of muscle memory, your groups will become tighter and consistent. Then you will be ready. Cheers!

Matthew, Quick, accurate follow up shots can be a challenge if you don't really have hold of it. Take your time to recover grip and sight picture you will have no problem. 2 1/2" barrel is nice to carry hiking, but for up close and nasty business.