Stephen, unfortunately no, you cannot shoot 22lr threw the 22 mag cylinder. You would have to purchase the 22lr cylinder in order to shoot 22lr. I'd give the manufacturer a call at 1-800-821-5783 to see if they'll sell you one separately. Sorry but hope this helps.

Stephen, no sir, you would need the .22lr cylinder, which appears to be sold only with the combo. https://northamericanarms.com/shop/firearms/naa-22msc-tw/ ....I would contact NAA at 1-800-821-5783 or email info@northamericanarms.com to see if this can be purchased separately.

As mentioned below you'd need to have the 22LR cylinder.

Stephen, only if you get a separate 22LR Cylinder Sir (22lr cannot be fired from a 22Mag Cylinder) : https://northamericanarms.com/shop/firearms/naa-22msc-tw/