BudsGunShop.com - Will this fit a 10mm?

No, but for a different reason than the other answer. The shield is a slimline model that uses single stack magazines and doesn't have much in common with the regular M&P pistols. Mission First doesn't make the Minimalist model holster for the full-size S&W pistols but among their other models the 9mm, .40, and 10mm pistols should all fit the same if they are made for the appropriate barrel length or have an open bottom. So I think the closest would be something like this (which isn't in stock unfortunately, you might look elsewhere): budsgunshop.com/product_info.php/products_id/723006776/mission+first+tactical+ambidextrous+appendix+iwb+owb+holster+smith+%26+wesson+m%26p+2.0+9mm+40+caliber+right+hand+black

Hi Tanner, unfortunately your M&P 2.0 10mm will not fit in this holster.
Stay safe & have a great day!

Hi Tanner and welcome. No, the 10mm Slide has a wider diameter slide and frame. Cheers and stay safe!

sorry it only fits the 9mm and the 40 the 10mm is a larger gun